Emmet O'Reilly


 
researcher

Biography

Emmet is currently a lecturer in polymer/organic chemistry in the Department of Chemical Sciences and the course director for the BSc in Pharmaceutical and Industrial Chemistry. He completed his undergraduate studies (Analytical Science - DCU) in 2004 and doctoral studies in 2008 (PhD in Polymer Chemistry - Biomedical Diagnostics Institute - DCU). In 2010 he was awarded an Marie Curie post-doctoral fellowship and took up a position with the CNRS in Montpellier, France, returning to Ireland in 2013. 

Emmet's research involves investigating novel polymeric materials for applications in bio-sensing and pharmaceutical processing. He has extensive experience in polymer characterization and synthesis of electroactive polymeric materials. He is an active member of the Bernal Institute currently leading a group of 7 researchers at the including 2 Marie Curie Research Fellows, 1 Post-doctoral researcher and 4 postgraduate students. He as co-authored multiple peer reviewed articles and acts as an international accreditation assessor for the Royal Society of Chemistry. 

Research Interests

My research focuses on the design, synthesis and characterisation of stimuli-responsive polymeric materials for biomedical and pharmaceutical applications. 

Specific research strands include; 
  • Synthesis of bio-degradable electroactive polymeric materials for in-vitro/in-vivo diagnostics and disposable electronics. 
  • Hydrogel/Silicone porous materials with tunable mechanical properties.
  • Novel polymeric materials/processing approaches for improved pharmaceutics.
Core competencies include;
  • Polymer synthesis/characterisation/functionalisation.
  • Electrochemistry and Electrochemiluminescence (ECL).
  • Spray-drying, NMR, Mass Spectroscopy, Electrochemistry. 
Research is currently funded by Science Foundation Ireland, Enterprise Ireland, EU-Commission and the Irish Research Council. 

Peer Reviewed Journals

  Year Publication
2020 'A rational approach towards spray drying of biopharmaceuticals: The case of lysozyme'
Ziaee A.;Albadarin A.B.;Padrela L.;Ung M.T.;Femmer T.;Walker G.;O'Reilly E. (2020) 'A rational approach towards spray drying of biopharmaceuticals: The case of lysozyme'. Powder Technology, 366 :206-215 [DOI] [Details]
2019 'Co-crystal polymorphic control by nanodroplet and electrical confinement'
Padrela L.;Castro-Dominguez B.;Ziaee A.;Long B.;Ryan K.;Walker G.;O'Reilly E. (2019) 'Co-crystal polymorphic control by nanodroplet and electrical confinement'. Crystengcomm, 21 (18):2845-2848 [DOI] [Details]
2019 'Synthesis and Characterization of CuZnSe2 Nanocrystals in Wurtzite, Zinc Blende, and Core-Shell Polytypes'
Ren H.;Wang M.;Li Z.;Laffir F.;Brennan G.;Sun Y.;Stokes K.;Geaney H.;O'Reilly E.;Gao P.;Liu N.;McCarthy C.;Ryan K. (2019) 'Synthesis and Characterization of CuZnSe2 Nanocrystals in Wurtzite, Zinc Blende, and Core-Shell Polytypes'. Chemistry Of Materials, [DOI] [Details]
2019 'Impact of polymeric excipient on cocrystal formation via hot-melt extrusion and subsequent downstream processing'
Karimi-Jafari M.;Ziaee A.;Iqbal J.;O'Reilly E.;Croker D.;Walker G. (2019) 'Impact of polymeric excipient on cocrystal formation via hot-melt extrusion and subsequent downstream processing'. International journal of pharmaceutics, 566 :745-755 [DOI] [Details]
2019 'Rapid microwave assisted synthesis and characterisation of a semiconducting polymer with pK a tuneable degradation properties'
Heffernan M.;O'Reilly E. (2019) 'Rapid microwave assisted synthesis and characterisation of a semiconducting polymer with pK a tuneable degradation properties'. European Polymer Journal, 114 :206-212 [DOI] [Details]
2019 'Particle engineering of excipients: A mechanistic investigation into the compaction properties of lignin and [co]-spray dried lignin'
Solomon S.;Ziaee A.;Giraudeau L.;O'Reilly E.;Walker G.;Albadarin A. (2019) 'Particle engineering of excipients: A mechanistic investigation into the compaction properties of lignin and [co]-spray dried lignin'. International journal of pharmaceutics, 563 :237-248 [DOI] [ULIR Link] [Details]
2018 'Spray drying of pharmaceuticals and biopharmaceuticals: Critical parameters and experimental process optimization approaches'
Ziaee A;Albadarin AB;Padrela L;Femmer T;O'Reilly E;Walker G; (2018) 'Spray drying of pharmaceuticals and biopharmaceuticals: Critical parameters and experimental process optimization approaches'. European Journal Of Pharmaceutical Sciences : Official Journal Of The European Federation For Pharmaceutical Sciences, [DOI] [Details]
2017 'Spray drying ternary amorphous solid dispersions of ibuprofen - An investigation into critical formulation and processing parameters'
Ziaee, A,Albadarin, AB,Padrela, L,Faucher, A,O'Reilly, E,Walker, G (2017) 'Spray drying ternary amorphous solid dispersions of ibuprofen - An investigation into critical formulation and processing parameters'. European Journal Of Pharmaceutics And Biopharmaceutics, 120 :43-51 [DOI] [Details]
2017 'Temperature controlled shape evolution of iron oxide nanostructures in HMTA media'
Zhao, B,Ryan, KM,O'Reilly, E,McCarthy, C (2017) 'Temperature controlled shape evolution of iron oxide nanostructures in HMTA media'. Rsc Advances, 7 :26328-26334 [DOI] [ULIR Link] [Details]
2016 'Formation of reworkable nanocomposite adhesives by dielectric heating of epoxy resin embedded Fe3O4 hollow spheres'
Zhao, B,Hardiman, M,Ryan, KM,O'Reilly, E,McCarthy, C (2016) 'Formation of reworkable nanocomposite adhesives by dielectric heating of epoxy resin embedded Fe3O4 hollow spheres'. Crystengcomm, 18 :6096-6101 [DOI] [ULIR Link] [Details]
2015 'Electrochemiluminescence platform for the detection of C-reactive proteins: application of recombinant antibody technology to cardiac biomarker detection'
O'Reilly, E.J., Conroy, P.J., Hearty, S., Keyes, T.E., O'Kennedy, R., Forster, R.J., Dennany, L. (2015) 'Electrochemiluminescence platform for the detection of C-reactive proteins: application of recombinant antibody technology to cardiac biomarker detection'. Rsc Advances, [Details]
2014 'The application of water soluble, mega-Stokes-shifted BODIPY fluorophores to cell and tissue imaging'
Moriarty R.;Martin A.;Adamson K.;O'Reilly E.;Mollard P.;Forster R.;Keyes T. (2014) 'The application of water soluble, mega-Stokes-shifted BODIPY fluorophores to cell and tissue imaging'. Journal Of Microscopy, 253 (3):204-218 [DOI] [Details]
2015 'A Cholesterol Biosensor Based on the NIR Electrogenerated-Chemiluminescence (ECL) of Water-Soluble CdSeTe/ZnS Quantum Dots'
Stewart, A.J., O'Reilly, E.J., Moriarty, R.D., Bertoncello, P., Keyes, T.E., Forster, R.J., Dennany, L. (2015) 'A Cholesterol Biosensor Based on the NIR Electrogenerated-Chemiluminescence (ECL) of Water-Soluble CdSeTe/ZnS Quantum Dots'. Electrochimica Acta, [Details]
2014 'The application of water soluble, mega-Stokes-shifted BODIPY fluorophores to cell and tissue imaging'
Moriarty, R.D., Martin, A., Adamson, K., O'Reilly, E., Mollard, P., Forster, R.J., Keyes, T.E. (2014) 'The application of water soluble, mega-Stokes-shifted BODIPY fluorophores to cell and tissue imaging'. Journal Of Microscopy, [Details]
2013 'Insights into electrochemiluminescent enhancement through electrode surface modification'
O'Reilly, E.J., Keyes, T.E., Forster, R.J., Dennany, L. (2013) 'Insights into electrochemiluminescent enhancement through electrode surface modification'. Analyst, [Details]
2013 'Electrochemically induced release of a luminescent probe from a rhenium-containing metallopolymer'
Valenti, G., O'Reilly, E.J., McNally, A., Keyes, T.E., Marcaccio, M., Paolucci, F., Forster, R.J. ChemPlusChem (2013) 'Electrochemically induced release of a luminescent probe from a rhenium-containing metallopolymer'. Chembiochem, [Details]
2011 'Demonstration of surface plasmon-coupled emission using solid-state electrochemiluminescence'
Yuk, J.S., O'Reilly, E., Forster, R.J., MacCraith, B.D., McDonagh, C. (2011) 'Demonstration of surface plasmon-coupled emission using solid-state electrochemiluminescence'. Chemical Physics Letters, [Details]
2011 'Ground and excited state communication within a ruthenium containing benzimidazole metallopolymer'
O'Reilly, E.J., Dennany, L., Griffith, D., Moser, F., Keyes, T.E., Forster, R.J. (2011) 'Ground and excited state communication within a ruthenium containing benzimidazole metallopolymer'. Pccp Physical Chemistry Chemical Physics, [Details]
2011 'Chronocoulometric determination of urea in human serum using an inkjet printed biosensor'
Suman, O'Reilly, E., Kelly, M., Morrin, A., Smyth, M.R., Killard, A.J. (2011) 'Chronocoulometric determination of urea in human serum using an inkjet printed biosensor'. Analytica Chimica Acta, [Details]
2009 'The influence of poly(2-methoxyaniline-5-sulfonic acid) on the electrochemical and photochemical properties of a highly luminescent ruthenium complex'
Dennany, L., O'Reilly, E.J., Innis, P.C., Wallace, G.G., Forster, R.J. (2009) 'The influence of poly(2-methoxyaniline-5-sulfonic acid) on the electrochemical and photochemical properties of a highly luminescent ruthenium complex'. Electrochimica Acta, [Details]
2009 'Solid state photochemistry of novel composites containing luminescent metal centers and poly(2-methoxyaniline-5-sulfonic acid)'
Dennany, L., O'Reilly, E.J., Innis, P.C., Wallace, G.G., Forster, R.J. (2009) 'Solid state photochemistry of novel composites containing luminescent metal centers and poly(2-methoxyaniline-5-sulfonic acid)'. Journal Of Physical Chemistry B, [Details]
2006 'Electrochemiluminescent monolayers on metal oxide electrodes: Detection of amino acids'
Dennany, L., O'Reilly, E.J., Keyes, T.E., Forster, R.J. (2006) 'Electrochemiluminescent monolayers on metal oxide electrodes: Detection of amino acids'. Electrochemistry Communications, [Details]

Conference Publications

  Year Publication
2007 324th Meeting of the American Chemical Society
Lynn Dennany, Emmet J O'Reilly, Peter C Innis, Gordon Wallace, Robert J Forster (2007) Photoinduced electron and energy transfer processes between a ruthenium moiety and a conducting polymer 324th Meeting of the American Chemical Society [Details]
2012 Lauret Imaging
O’Reilly, E.J., Molino, F., Lafont, C., Mollard, P., (2012) The creation of 3-Dimensional Reconstructions using novel fluorescent dyes Lauret Imaging [Details]

Conference Contributions

  Year Publication
2016 International Dairy Federation,
Mahsa Naghshineh*, Harry Van den Akker, Emmet O‘Reilly and Gavin M. Walker (2016) Simulation of Laboratory-Scale Spray Drying of Skimmed Milk Using Computational Fluid Dynamics. [Poster Presentation], International Dairy Federation, Dublin , 11-APR-16 - 14-APR-16 [Details]
2016 International Dairy Federation,
Dr Akeem Olaleye, Prof Harry Van Den Akker, Prof Gavin Walker, Dr. Emmet O'Reilly, Dr Kevin Cronin (2016) Optimizing Pneumatic Conveying Conditions of Dairy Powders: A Multi-scale Modelling Approach. [Poster Presentation], International Dairy Federation, Dublin, Ireland , 11-APR-16 - 14-APR-16 [Details]
2015 5th annual NUIG-UL Postgraduate Research day,
O'Reilly., E (2015) Conducting polymers as transduction mechanisms in biomedical sensing platforms. [Invited Lecture], 5th annual NUIG-UL Postgraduate Research day, National University of Ireland, Galway , 21-APR-15 - 21-APR-15 [Details]
2012 1st Lauret Imaging meeting 2012,
O’Reilly, E.J., Molino, F., Lafont, C., Mollard, P., (2012) The creation of 3-Dimensional Reconstructions using novel fluorescent dyes’. [Oral Presentation], 1st Lauret Imaging meeting 2012, Lauret, France , 17-FEB-12 - 18-SEP-13 [Details]
2008 International Electromaterials Science Symposium, CSIRO,
Dennany, L., O’Reilly, E.J., Innis, P.C., Wallace, G.G., Forster, R.J., (2008) Influence of a conducting polymer on the properties of a ruthenium moiety’. [Poster Presentation], International Electromaterials Science Symposium, CSIRO, Melbourne, Australia , 21-FEB-08 - 22-FEB-08 [Details]
2008 234th American Chemical Society (ACS) International Meeting,
Emmet O'Reilly (2008) Electrochemiluminescent Materials for Biomedical Detection. [Oral Presentation], 234th American Chemical Society (ACS) International Meeting, Boston, MA , 19-AUG-08 - 23-JUL-14 [Details]
2008 Polymers Down-under Makes Irish Sense,
O’Reilly, E.J., Forster, R.J., Wallace, G.G., (2008) Metallopolymer composites for use in Biomedical Diagnostics; Electrochemiluminescent Applications’. [Oral Presentation], Polymers Down-under Makes Irish Sense, Dublin City University, Dublin, Ireland , 18-SEP-08 - 19-SEP-08 [Details]
2007 International Society of Electrochemistry,,
O’Reilly, E., Dennany, L., Forster., (2007) Electrochemical and Photophysical characterisation of a ruthenium containing conjugated metallopolymer. [Oral Presentation], International Society of Electrochemistry,, Dublin City University , 07-MAY-07 - 09-MAY-07 [Details]
2007 210th Meeting of The Electrochemical Society,,
O’Reilly, E.J., Dennany, L., Keyes, T.E., Forster R.J., (2007) Conducting Metallopolymer composites for use in Biomedical Diagnostics’. [Oral Presentation], 210th Meeting of The Electrochemical Society,, Cancun, Mexico , 29-OCT-07 - 03-NOV-07 [Details]
2014 ECL 2014 International Meeting on Electrogenerated Chemiluminescence,
O’Reilly, E., Dennany, L., Forster. R., (2014) Combining Recombinant Antibody technology and electrochemiluminescent sensing platforms for Cardiac Biomarker detection. Current approaches and perspectives. [Oral Presentation], ECL 2014 International Meeting on Electrogenerated Chemiluminescence, Bologna, Italy , 07-SEP-14 - 10-APR-14 [Details]
2007 234th American Chemical Society (ACS) International Meeting,
O’Reilly, E.J., Dennany, L., Innis, P.C., Wallace, G.G., Forster R.J., (2007) Novel Electrochemiluminescent Materials for Biomedical Detection’. [Chaired Session], 234th American Chemical Society (ACS) International Meeting, Boston, MA, USA , 19-AUG-07 - 23-AUG-07 [Details]
2006 International Conference on Synthetic Metals (ICSM),
O’Reilly, E.J., Dennany, L., Innis, P.C., Masdarolomoor, F., Wallace, G.G., Forster, R.J., (2006) ‘The Influence of Poly(2-methoxyaniline-5-sulfonic acid) on the Electrochemical and Photochemical Properties Of a Highly Luminescent Ruthenium Complex’. [Poster Presentation], International Conference on Synthetic Metals (ICSM), Trinity College Dublin , 02-JUL-06 - 07-JUL-06 [Details]
2005 Electrochem 2005,
O’Reilly, E.J., Dennany, L., Griffith, D., Keyes, T.E., Forster, R.J., (2005) Photonic Properties of Conjugated Metallopolymers’. [Chaired Session], Electrochem 2005, University of Northumbria, Newcastle upon Tyne , 04-SEP-05 - 07-SEP-06 [Details]

Honours and Awards

  Year Title Awarding Body
2010 Marie Curie Fellowship Irish Research Council

Professional Associations

  Association Function From / To
Royal Society of Chemistry Associate Member (AMRSC) 19-APR-13 / 18-AUG-18

Committees

  Committee Function From / To
S&E Research Committee CES Representative 2014 / 2016
CES Safety Committee Academic Representative 2013 / 2016

Employment

  Employer Position From / To
IPSEN Pharmaceuticals Quality Control Analyst /

Education

  Year Institution Qualification Subject
2008 Biomedical Diagnostics Institute - Dublin City University PhD Polymer Chemistry
2015 University of Limerick Specialist Diploma in Teaching, Learning and Scholarship Specialist diploma
2004 Dublin City University BSc (Hons) Analytical Science

Languages

  Language Reading Writing Speaking
French Functional Functional Functional

Teaching Interests

Course Director: BSc. Pharmaceutical and Industrial Chemistry 

                         
Current modules: 
CH4103 Organic Chemistry 2A
CH4015 Organic Chemistry 4
CH4306 Analytical Chemistry 4
BC4401 Introduction to Biochemistry  

Modules Taught

  Term (ID)) Title Link Subject
Organic Chemistry 2A CH4103
Introductory Biochemistry BC4401
Organic Chemistry 4 CH4015

International Collaborators

  Name Organisation / Institute Country
Conor Hogan La Trobe University Australia
Lynn Dennany University of Strathclyde Scotland
Paul Conroy Monash University Australia
Paolo Bertoncello Swansea University Wales
Patrice Mollard Institut de Génomique Fonctionnelle (IGF) France
Paolo Bertoncello Swansea University Wales