Sarah Hudson


 
researcher

Biography

Sarah studied Chemistry in Trinity College Dublin were she was a Trinity Foundation Scholar and where she did a research masters on the synthesis of a family of Re (I) metal complexes and a study of their photophysical properties with Prof John Kelly. Her PhD in the University of Limerick focussed on the immobilization of enzymes onto novel mesoporous supports and their catalytic properties with Prof Edmond Magner, Prof Kieran Hodnett and Dr Jakki Cooney. She secured a Marie Curie Outgoing International Fellowship to work with Prof Robert Langer in MIT, USA. There she developed in situ crosslinkable hydrogel systems for cartilage regeneration and drug delivery and she also studied the biocompatibility (in vivo and in vitro) of micro- and nano- mesoporous silica particles. After this fellowship, Sarah worked in Waterford Institute of Technology on the identification of the mechanisms and causes of tablet splitting within the Genzyme Ireland facility. Since November 2011, Sarah has been a lecturer in Chemistry in the Department of Chemical Sciences and a researcher in the Bernal Institute in the University of Limerick. She is a principal investigator in the Science Foundation Ireland Research Centre for Pharmaceuticals (SSPC) since 2013.

 

Research Interests


The Hudson group focuses on the manipulation of the physicochemical properties of small and large active molecules to improve their stability, solubility and dissolution rates with the ultimate goal of improving the bioavailability of active pharmaceutical ingredients. They explore the solution and solid state behaviour of these molecules both during formulation/manufacture into medicines and in biorelevant environments. Their research focuses on the thermodynamics behind aggregation, crystallisation and precipitation in a range of solvents and bio relevant media and develops formulations and structures to control this solution/solid state behaviour. 

Current Postdoctoral researchers:
Dr Jhimli Paulguin
Dr Poonam Ratrey
Dr Shasha Jin

Current PhD students:
Mariana Silva (Marie Curie ITN, Janssen)
Amabille Kloc (Marie Curie ITN, TUD, Janssen)
Peuli Ghosh (SFI, SSPC)
Parth Joshi (PMTC, Allergen)
Mariana Diniz (SFI, SSPC)
Marta Bergillos (SFI, SSPC)
Harsh Barua (SFI, SSPC)
Camila Viera (SFI, New Frontiers)
Mateo Flores Naranjo (SFI, New Frontiers)
Francisco Duarte (IRC)
Sara Fatima (SFI, co-supervised with Jennifer Cookman)

Former PhD students:
Dr Teresa Tierney (IRCSET, SSPC)
Dr Raquel Arribas Bueno (SFI SSPC)
Dr Pauric Bannigan (SFI CDA) 
Dr Vivek Verma (SFI SSPC)
Dr Katalin Bodnar (SFI SSPC)
Dr Ajay Kumar (SFI, SSPC)
Dr Michele Dully (IRC, COOK Medical)
Dr James Flynn (SFI, CDA)
Dr Sally Ryan (SFI, Curam)
Dr Miriama Ceresnakova (IRC, COOK Medical)
Dr Aoibhin Ryan (IRC)

Former Masters students: 
Sarah Mallen (SFI CDA) 
Tracey Carroll (Sanofi Genzyme)
 
Former Postdocs:
Dr Gesmi Mikovich (SFI CDA)
Dr Edel Durack (SFI CDA)
Dr Aisling Lynch (SFI SSPC)
Dr Ajay Kumar (SFI, SSPC)
Dr Malgorzata Tecza (DTIF, EI)
Dr Pratikkumar Patel
Dr Promita Bhattacharjee
Dr Vinay Gedi 

Peer Reviewed Journals

  Year Publication
2023 'Production of hydrochlorothiazide nanoparticles with increased permeability using top-spray coating process'
Verma, V;Patel, P;Ryan, KM;Hudson, S;Padrela, L (2023) 'Production of hydrochlorothiazide nanoparticles with increased permeability using top-spray coating process'. Journal Of Supercritical Fluids, 192 [DOI] [Details]
2023 'The development of a solid lipid nanoparticle (SLN)-based lacticin 3147 hydrogel for the treatment of wound infections'
Ryan A.;Patel P.;Ratrey P.;O¿Connor P.M.;O¿Sullivan J.;Ross R.P.;Hill C.;Hudson S.P. (2023) 'The development of a solid lipid nanoparticle (SLN)-based lacticin 3147 hydrogel for the treatment of wound infections'. Drug Delivery And Translational Research, [DOI] [Details]
2023 'Identification of monoclonal antibody drug substances using non-destructive Raman spectroscopy'
Shukla M.K.;Wilkes P.;Bargary N.;Meagher K.;Khamar D.;Bailey D.;Hudson S.P. (2023) 'Identification of monoclonal antibody drug substances using non-destructive Raman spectroscopy'. Spectrochimica Acta Part A-Molecular And Biomolecular Spectroscopy, 299 [DOI] [Details]
2023 'Impact of Propeptide Cleavage on the Stability and Activity of a Streptococcal Immunomodulatory C5a Peptidase for Biopharmaceutical Development'
Gedi V.;Duarte F.;Patel P.;Bhattacharjee P.;Tecza M.;McGourty K.;Hudson S.P. (2023) 'Impact of Propeptide Cleavage on the Stability and Activity of a Streptococcal Immunomodulatory C5a Peptidase for Biopharmaceutical Development'. Molecular Pharmaceutics, [DOI] [Details]
2023 'Production of hydrochlorothiazide nanoparticles with increased permeability using top-spray coating process'
Verma V.;Patel P.;Ryan K.M.;Hudson S.;Padrela L. (2023) 'Production of hydrochlorothiazide nanoparticles with increased permeability using top-spray coating process'. Journal Of Supercritical Fluids, 192 [DOI] [Details]
2022 'The impact of varying dextran oxidation levels on the inhibitory activity of a bacteriocin loaded injectable hydrogel'
Flynn J.;Culebras M.;Collins M.N.;Hudson S.P. (2022) 'The impact of varying dextran oxidation levels on the inhibitory activity of a bacteriocin loaded injectable hydrogel'. Drug Delivery And Translational Research, [DOI] [Details]
2022 'Impact of Excipients and Seeding on the Solid-State Form Transformation of Indomethacin during Liquid Antisolvent Precipitation'
Hugo Silva M.;Kumar A.;Hodnett B.K.;Tajber L.;Holm R.;Hudson S.P. (2022) 'Impact of Excipients and Seeding on the Solid-State Form Transformation of Indomethacin during Liquid Antisolvent Precipitation'. Crystal Growth & Design, 22 (10):6056-6069 [DOI] [Details]
2022 'Long acting injectables for therapeutic proteins'
Ryan S.;Shortall K.;Dully M.;Djehedar A.;Murray D.;Butler J.;Neilan J.;Soulimane T.;Hudson S.P. (2022) 'Long acting injectables for therapeutic proteins'. Colloids and surfaces. B, Biointerfaces, 217 [DOI] [Details]
2022 'Solubility, aggregation and stability of Amphotericin B drug in pure organic solvents: Thermodynamic analysis and solid form characterization'
Soto R.;Patel P.;Albadarin A.B.;Diniz M.O.;Hudson S.P. (2022) 'Solubility, aggregation and stability of Amphotericin B drug in pure organic solvents: Thermodynamic analysis and solid form characterization'. Journal Of Molecular Liquids, 366 [DOI] [Details]
2022 'Single versus double occupancy solid lipid nanoparticles for delivery of the dual-acting bacteriocin, lacticin 3147'
Ryan A;Patel P;O'Connor PM;Cookman J;Paul Ross R;Hill C;Hudson SP; (2022) 'Single versus double occupancy solid lipid nanoparticles for delivery of the dual-acting bacteriocin, lacticin 3147'. European Journal Of Pharmaceutics And Biopharmaceutics, [DOI] [Details]
2022 'Balanced lipase interactions for degradation-controlled paclitaxel release from lipid cubic phase formulations'
Dully, M;Bhattacharya, S;Verma, V;Murray, D;Thompson, D;Soulimane, T;Hudson, SP (2022) 'Balanced lipase interactions for degradation-controlled paclitaxel release from lipid cubic phase formulations'. Journal of colloid and interface science, 607 :978-991 [DOI] [Details]
2022 'Synergistic antimicrobial interactions of nisin A with biopolymers and solubilising agents for oral drug delivery'
Flynn J.;Ryan A.;Hudson S.P. (2022) 'Synergistic antimicrobial interactions of nisin A with biopolymers and solubilising agents for oral drug delivery'. European Journal Of Pharmaceutics And Biopharmaceutics, 171 :29-38 [DOI] [Details]
2022 'Osmolality of Excipients for Parenteral Formulation Measured by Freezing Point Depression and Vapor Pressure ¿ A Comparative Analysis'
Hugo Silva M.;Hudson S.P.;Tajber L.;Garin M.;Dong W.;Khamiakova T.;Holm R. (2022) 'Osmolality of Excipients for Parenteral Formulation Measured by Freezing Point Depression and Vapor Pressure ¿ A Comparative Analysis'. Pharmaceutical Research, [DOI] [Details]
2022 'The influence of poly(allylamine hydrochloride) hydrogel crosslinking density on its thermal and phosphate binding properties'
Elsiddig R.;O'Reilly N.J.;Hudson S.P.;Owens E.;Hughes H.;O'Grady D.;McLoughlin P. (2022) 'The influence of poly(allylamine hydrochloride) hydrogel crosslinking density on its thermal and phosphate binding properties'. International journal of pharmaceutics, 621 [DOI] [Details]
2022 'NUIG4: A biocompatible pcu metal-organic framework with an exceptional doxorubicin encapsulation capacity'
Ahmed A.;Efthymiou C.G.;Sanii R.;Patyk-Kazmierczak E.;Alsharabasy A.M.;Winterlich M.;Kumar N.;Sensharma D.;Tong W.;Guerin S.;Farras P.;Hudson S.;Thompson D.;Zaworotko M.J.;Tasiopoulos A.J.;Papatriantafyllopoulou C. (2022) 'NUIG4: A biocompatible pcu metal-organic framework with an exceptional doxorubicin encapsulation capacity'. Journal Of Materials Chemistry B, 10 (9):1378-1385 [DOI] [Details]
2021 'Candidates for smart cardiovascular medical device coatings: A comparative study with endothelial and smooth muscle cells'
Ceresnakova, M;Murray, D;Soulimane, T;Hudson, SP (2021) 'Candidates for smart cardiovascular medical device coatings: A comparative study with endothelial and smooth muscle cells'. European Journal Of Pharmacology, 910 [DOI] [Details]
2021 'Stent conditioned media for in vitro evaluation of hydrophobic stent coatings'
Ceresnakova, M;Dully, M;Murray, D;Soulimane, T;Hudson, SP (2021) 'Stent conditioned media for in vitro evaluation of hydrophobic stent coatings'. Toxicology In Vitro, 76 [DOI] [Details]
2021 'Lipid Cubic Systems for Sustained and Controlled Delivery of Antihistamine Drugs'
Dully, M;Ceresnakova, M;Murray, D;Soulimane, T;Hudson, SP (2021) 'Lipid Cubic Systems for Sustained and Controlled Delivery of Antihistamine Drugs'. Molecular Pharmaceutics, 18 :3777-3794 [DOI] [Details]
2021 'Pharmaceutical design of a delivery system for the bacteriocin lacticin 3147'
Ryan, A;Patel, P;O'Connor, PM;Ross, RP;Hill, C;Hudson, SP (2021) 'Pharmaceutical design of a delivery system for the bacteriocin lacticin 3147'. Drug Delivery And Translational Research, 11 :1735-1751 [DOI] [Details]
2021 'Pre-formulation and delivery strategies for the development of bacteriocins as next generation antibiotics'
Flynn, J;Ryan, A;Hudson, SP (2021) 'Pre-formulation and delivery strategies for the development of bacteriocins as next generation antibiotics'. European Journal Of Pharmaceutics And Biopharmaceutics, 165 :149-163 [DOI] [Details]
2021 'Citric acid functionalized nitinol stent surface promotes endothelial cell healing'
Ceresnakova M;Murray D;McGourty KD;Butler J;Neilan J;Soulimane T;Hudson SP; (2021) 'Citric acid functionalized nitinol stent surface promotes endothelial cell healing'. Journal Of Biomedical Materials Research Part A, [DOI] [ULIR Link] [Details]
2021 'Preparation, stabilisation, isolation and tableting of valsartan nanoparticles using a semi-continuous carrier particle mediated process'
Kumar A;Ramisetty KA;Bordignon S;Hodnett BK;Davern P;Hudson S; (2021) 'Preparation, stabilisation, isolation and tableting of valsartan nanoparticles using a semi-continuous carrier particle mediated process'. International journal of pharmaceutics, 597 [DOI] [Details]
2020 'Modification of the zeta potential of montmorillonite to achieve high active pharmaceutical ingredient nanoparticle loading and stabilization with optimum dissolution properties'
Kumar A.;Hodnett B.K.;Hudson S.;Davern P. (2020) 'Modification of the zeta potential of montmorillonite to achieve high active pharmaceutical ingredient nanoparticle loading and stabilization with optimum dissolution properties'. Colloids and surfaces. B, Biointerfaces, 193 [DOI] [ULIR Link] [Details]
2020 'Tuning the strength and swelling of an injectable polysaccharide hydrogel and the subsequent release of a broad spectrum bacteriocin, nisin A'
Flynn J.;Durack E.;Collins M.N.;Hudson S.P. (2020) 'Tuning the strength and swelling of an injectable polysaccharide hydrogel and the subsequent release of a broad spectrum bacteriocin, nisin A'. Journal Of Materials Chemistry B, 8 (18):4029-4038 [DOI] [Details]
2020 'Modulating the release of pharmaceuticals from lipid cubic phases using a lipase inhibitor'
Dully M.;Brasnett C.;Djeghader A.;Seddon A.;Neilan J.;Murray D.;Butler J.;Soulimane T.;Hudson S.P. (2020) 'Modulating the release of pharmaceuticals from lipid cubic phases using a lipase inhibitor'. Journal of colloid and interface science, 573 :176-192 [DOI] [Details]
2020 'Drug Loading and Dissolution Properties of Dalcetrapib-Montmorillonite Nanocomposite Microparticles'
Bodnár K.;Hudson S.P.;Rasmuson Å.C. (2020) 'Drug Loading and Dissolution Properties of Dalcetrapib-Montmorillonite Nanocomposite Microparticles'. Organic Process Research &Amp; Development, 24 (6):977-987 [DOI] [Details]
2019 'Overcoming the Common Ion Effect for Weakly Basic Drugs: Inhibiting the Crystallization of Clofazimine Hydrochloride in Simulated Gastrointestinal Media'
Bannigan P.;Verma V.;Hudson S. (2019) 'Overcoming the Common Ion Effect for Weakly Basic Drugs: Inhibiting the Crystallization of Clofazimine Hydrochloride in Simulated Gastrointestinal Media'. Crystal Growth & Design, [DOI] [ULIR Link] [Details]
2008 'Proteins in mesoporous silicates'
Hudson, S.;Cooney, J.;Magner, E.; (2008) 'Proteins in mesoporous silicates'. Angew Chem Int Ed Engl, [DOI] [Details]
2005 'Methodology for the immobilization of enzymes onto mesoporous materials'
Hudson, S.;Magner, E.;Cooney, J.;Hodnett, B. K.; (2005) 'Methodology for the immobilization of enzymes onto mesoporous materials'. J Phys Chem B, [DOI] [Details]
2019 'Protecting bactofencin A to enable its antimicrobial activity using mesoporous matrices'
Durack, E;Mallen, S;O'Connor, PM;Rea, MC;Ross, RP;Hill, C;Hudson, S (2019) 'Protecting bactofencin A to enable its antimicrobial activity using mesoporous matrices'. International journal of pharmaceutics, 558 :9-17 [DOI] [Details]
2019 'Nitrogen and sulfur co-doped carbon nanodots toward bovine hemoglobin: A fluorescence quenching mechanism investigation'
Wang J.;Xiang X.;Milcovich G.;Chen J.;Chen C.;Feng J.;Hudson S.;Weng X.;Ruan Y. (2019) 'Nitrogen and sulfur co-doped carbon nanodots toward bovine hemoglobin: A fluorescence quenching mechanism investigation'. Journal Of Molecular Recognition, 32 (2) [DOI] [Details]
2019 'Mesoporous matrices for the delivery of the broad spectrum bacteriocin, nisin A'
Flynn, J;Mallen, S;Durack, E;O'Connor, PM;Hudson, SP (2019) 'Mesoporous matrices for the delivery of the broad spectrum bacteriocin, nisin A'. Journal of colloid and interface science, 537 :396-406 [DOI] [Details]
2019 'Promotion of Mefenamic Acid Nucleation by a Surfactant Additive, Docusate Sodium'
Bodnár K.;Hudson S.;Rasmuson Å. (2019) 'Promotion of Mefenamic Acid Nucleation by a Surfactant Additive, Docusate Sodium'. Crystal Growth & Design, 19 (2):591-603 [DOI] [Details]
2018 'Delivery of a hydrophobic drug into the lower gastrointestinal system via an endogenous enzyme-mediated carrier mechanism: An in vitro study'
Bannigan, P;Durack, E;Mathur, H;Rea, MC;Ross, RP;Hudson, SP (2018) 'Delivery of a hydrophobic drug into the lower gastrointestinal system via an endogenous enzyme-mediated carrier mechanism: An in vitro study'. European Journal Of Pharmaceutics And Biopharmaceutics, 133 :12-19 [DOI] [Details]
2018 'Dependence of Heterogeneous Nucleation on Hydrogen Bonding Lifetime and Complementarity'
Verma, V;Zeglinski, J;Hudson, S;Davern, P;Hodnett, BK (2018) 'Dependence of Heterogeneous Nucleation on Hydrogen Bonding Lifetime and Complementarity'. Crystal Growth & Design, 18 :7158-7172 [DOI] [ULIR Link] [Details]
2018 'Heterogeneous Crystallization of Fenofibrate onto Pharmaceutical Excipients'
Bueno, RA;Crowley, CM;Davern, P;Hodnett, BK;Hudson, S (2018) 'Heterogeneous Crystallization of Fenofibrate onto Pharmaceutical Excipients'. Crystal Growth & Design, 18 :2151-2164 [DOI] [Details]
2018 'Investigating the effects of amphipathic gastrointestinal compounds on the solution behaviour of salt and free base forms of clofazimine: An in vitro evaluation'
Bannigan, P;Stokes, K;Kumar, A;Madden, C;Hudson, SP (2018) 'Investigating the effects of amphipathic gastrointestinal compounds on the solution behaviour of salt and free base forms of clofazimine: An in vitro evaluation'. International journal of pharmaceutics, 552 :180-192 [DOI] [Details]
2019 'Carrier particle mediated stabilization and isolation of valsartan nanoparticles'
Kumar A;Davern P;Hodnett BK;Hudson SP; (2019) 'Carrier particle mediated stabilization and isolation of valsartan nanoparticles'. Colloids and surfaces. B, Biointerfaces, 175 [DOI] [Details]
2018 'The heterogeneous crystallization of a novel solvate of clozapine base in the presence of excipients'
Verma, V;Bannigan, P;Lusi, M;Crowley, CM;Hudson, S;Hodnett, BK;Davern, P (2018) 'The heterogeneous crystallization of a novel solvate of clozapine base in the presence of excipients'. Crystengcomm, 20 [DOI] [Details]
2018 'Co-reductive fabrication of carbon nanodots with high quantum yield for bioimaging of bacteria'
Wang, JJ,Liu, X,Milcovich, G,Chen, TY,Durack, E,Mallen, S,Ruan, YM,Weng, XX,Hudson, SP (2018) 'Co-reductive fabrication of carbon nanodots with high quantum yield for bioimaging of bacteria'. Beilstein Journal Of Nanotechnology, 9 :137-145 [DOI] [ULIR Link] [Details]
2018 'The heterogeneous crystallization of a novel solvate of clozapine base in the presence of excipients'
Verma, V;Bannigan, P;Lusi, M;Crowley, CM;Hudson, S;Hodnett, BK;Davern, P (2018) 'The heterogeneous crystallization of a novel solvate of clozapine base in the presence of excipients'. Crystengcomm, 20 :4370-4382 [DOI] [Details]
2017 'Role of Biorelevant Dissolution Media in the Selection of Optimal Salt Forms of Oral Drugs: Maximizing the Gastrointestinal Solubility and in Vitro Activity of the Antimicrobial Molecule, Clofazimine'
Bannigan, P,Durack, E,Madden, C,Lusi, M,Hudson, SP (2017) 'Role of Biorelevant Dissolution Media in the Selection of Optimal Salt Forms of Oral Drugs: Maximizing the Gastrointestinal Solubility and in Vitro Activity of the Antimicrobial Molecule, Clofazimine'. Acs Omega, 2 :8969-8981 [DOI] [ULIR Link] [Details]
2018 'Experimental Study on the Influence of Excipients on the Heterogeneous Crystallization and Dissolution Properties of an Active Pharmaceutical Ingredient'
Verma, V,Peddapatla, RVG,Crowley, CM,Crean, AM,Davern, P,Hudson, S,Hodnett, BK (2018) 'Experimental Study on the Influence of Excipients on the Heterogeneous Crystallization and Dissolution Properties of an Active Pharmaceutical Ingredient'. Crystal Growth & Design, 18 :338-350 [DOI] [ULIR Link] [Details]
2017 'Size and Shape Control of Micron-Sized Salicylic Acid Crystals during Antisolvent Crystallization'
Tierney, TB,Rasmuson, AC,Hudson, SP (2017) 'Size and Shape Control of Micron-Sized Salicylic Acid Crystals during Antisolvent Crystallization'. Organic Process Research & Development, 21 :1732-1740 [DOI] [Details]
2017 'Preparation and characterization of amorphous ciprofloxacin-amino acid salts'
Mesallati, H,Conroy, D,Hudson, S,Tajber, L (2017) 'Preparation and characterization of amorphous ciprofloxacin-amino acid salts'. European Journal Of Pharmaceutics And Biopharmaceutics, 121 :73-89 [DOI] [ULIR Link] [Details]
2017 'Influence of Process Parameters on the Heterogeneous Nucleation of Active Pharmaceutical Ingredients onto Excipients'
Bueno, RA,Crowley, CM,Hodnett, BK,Hudson, S,Davern, P (2017) 'Influence of Process Parameters on the Heterogeneous Nucleation of Active Pharmaceutical Ingredients onto Excipients'. Organic Process Research & Development, 21 :559-570 [DOI] [Details]
2017 'Carrier particle design for stabilization and isolation of drug nanoparticles'
Tierney, T,Bodnar, K,Rasmuson, A,Hudson, S (2017) 'Carrier particle design for stabilization and isolation of drug nanoparticles'. International journal of pharmaceutics, 518 :111-118 [DOI] [Details]
2017 'Stepwise Use of Additives for Improved Control over Formation and Stability of Mefenamic Acid Nanocrystals Produced by Antisolvent Precipitation'
Bodnar, K,Hudson, SP,Rasmuson, AC (2017) 'Stepwise Use of Additives for Improved Control over Formation and Stability of Mefenamic Acid Nanocrystals Produced by Antisolvent Precipitation'. Crystal Growth & Design, 17 :454-466 [DOI] [Details]
2015 'Investigating the solubility and cytocompatibility of CaO-Na2O-SiO2/TiO2 bioactive glasses'
Wren, AW,Coughlan, A,Smith, CM,Hudson, SP,Laffir, FR,Towler, MR (2015) 'Investigating the solubility and cytocompatibility of CaO-Na2O-SiO2/TiO2 bioactive glasses'. Journal Of Biomedical Materials Research Part A, 103 :709-720 [DOI] [Details]
2015 'Investigation of the Particle Growth of Fenofibrate following Antisolvent Precipitation and Freeze-Drying'
Tierney, TB,Guo, YN,Beloshapkin, S,Rasmuson, AC,Hudson, SP (2015) 'Investigation of the Particle Growth of Fenofibrate following Antisolvent Precipitation and Freeze-Drying'. Crystal Growth & Design, 15 :5213-5222 [DOI] [ULIR Link] [Details]
2016 'Recyclable SERS substrates based on Fe2O3-Ag hybrid hollow microspheres with crumpled surfaces'
Weng, XX,Feng, ZL,Guo, YN,Feng, JJ,Hudson, SP,Zheng, JF,Ruan, YM,Laffir, F,Pita, I (2016) 'Recyclable SERS substrates based on Fe2O3-Ag hybrid hollow microspheres with crumpled surfaces'. New Journal Of Chemistry, 40 :5238-5244 [DOI] [Details]
2016 'Investigation into the Solid and Solution Properties of Known and Novel Polymorphs of the Antimicrobial Molecule Clofazimine'
Bannigan, P,Zeglinski, J,Lusi, M,O'Brien, J,Hudson, SP (2016) 'Investigation into the Solid and Solution Properties of Known and Novel Polymorphs of the Antimicrobial Molecule Clofazimine'. Crystal Growth & Design, 16 :7240-7250 [DOI] [Details]
2012 'Enhancement and restriction of chain motion in polymer networks'
Hudson SP, Owens E, Hughes H, McLoughlin P (2012) 'Enhancement and restriction of chain motion in polymer networks'. International journal of pharmaceutics, 430 (1-2):34-41 [DOI] [Details]
2014 'Thermodynamics of fenofibrate and solubility in pure organic solvents'
Watterson, S,Hudson, S,Svard, M,Rasmuson, AC (2014) 'Thermodynamics of fenofibrate and solubility in pure organic solvents'. Fluid Phase Equilibria, 367 :143-150 [DOI] [Details]
2012 'Investigation of the Solid-State Polymorphic Transformations of Piracetam'
Maher, A,Seaton, CC,Hudson, S,Croker, DM,Rasmuson, AC,Hodnett, BK (2012) 'Investigation of the Solid-State Polymorphic Transformations of Piracetam'. Crystal Growth & Design, 12 :6223-6233 [DOI] [ULIR Link] [Details]
2012 'Enhancement and restriction of chain motion in polymer networks'
Hudson, SP,Owens, E,Hughes, H,McLoughlin, P (2012) 'Enhancement and restriction of chain motion in polymer networks'. International Journal Of Pharmaceutics, 430 :34-41 [DOI] [Details]
2011 'A Prototype Antifungal Contact Lens'
Ciolino, JB; Hudson, SP; Mobbs, AN; Hoare, TR; Iwata, NG; Fink, GR; Kohane, DS (2011) 'A Prototype Antifungal Contact Lens'. Investigative Ophthalmology & Visual Science, 52 :6286-6291 [DOI] [ULIR Link] [Details]
2011 'The bioactivity and ion release of titanium-containing glass polyalkenoate cements for medical applications'
Wren, AW; Cummins, NM; Laffir, FR; Hudson, SP; Towler, MR (2011) 'The bioactivity and ion release of titanium-containing glass polyalkenoate cements for medical applications'. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 22 (1):19-28 [DOI] [ULIR Link] [Details]
2011 'Defocus image contrast in hexagonally-ordered mesoporous material'
Nakahara, S; Tanner, DA; Hudson, S; Magner, E; Redington, W; Hodnett, K (2011) 'Defocus image contrast in hexagonally-ordered mesoporous material'. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 13 (3):1189-1200 [DOI] [ULIR Link] [Details]
2010 'Combinatorial extracellular matrices for human embryonic stem cell differentiation in 3D'
Yang F, Cho SW, Son SM, Hudson SP, Bogatyrev S, Keung L, Kohane DS, Langer R, Anderson DG (2010) 'Combinatorial extracellular matrices for human embryonic stem cell differentiation in 3D'. Biomacromolecules, 11 (8):1909-1914 [DOI] [Details]
2010 'Injectable in situ cross-linking hydrogels for local antifungal therapy'
Hudson, SP; Langer, R; Fink, GR; Kohane, DS (2010) 'Injectable in situ cross-linking hydrogels for local antifungal therapy'. BIOMATERIALS, 31 (6):1444-1452 [DOI] [ULIR Link] [Details]
2008 'Proteins in mesoporous silicates'
Hudson, S; Cooney, J; Magner, E (2008) 'Proteins in mesoporous silicates'. Angewandte Chemie-International Edition In English, 47 (45):8582-8594 [Details]
2008 'A nanoporous reactor for efficient proteolysis'
Qiao, L; Liu, Y; Hudson, SP; Yang, PY; Magner, E; Liu, BH (2008) 'A nanoporous reactor for efficient proteolysis'. CHEMISTRY-A EUROPEAN JOURNAL, 14 (1):151-157 [DOI] [Details]
2008 'A mesoporous reactor for high throughput proteolysis'
Qiao L; Liu, Y; Hudson, S; Yang, P; Magner, E; Liu, B (2008) 'A mesoporous reactor for high throughput proteolysis'. CHEMISTRY A EUROPEAN JOURNAL, 14 :151-157 [Details]
2008 'The biocompatibility of mesoporous silicates'
Hudson, SP; Padera, RF; Langer, R; Kohane, DS (2008) 'The biocompatibility of mesoporous silicates'. BIOMATERIALS, 29 (30):4045-4055 [DOI] [ULIR Link] [Details]
2007 'Chloroperoxidase on periodic mesoporous organosilanes: Immobilization and reuse'
Hudson, S; Cooney, J; Hodnett, BK; Magner, E (2007) 'Chloroperoxidase on periodic mesoporous organosilanes: Immobilization and reuse'. CHEMISTRY OF MATERIALS, 19 (8):2049-2055 [DOI] [Details]
2007 'Solvent dependent photophysics of fac-[Re(CO)(3)(11,12-X(2)dppz)(py)](+)(X = H, F or Me)'
Dyer J, Creely CM, Penedo JC, Grills DC, Hudson S, Matousek P, Parker AW, Towrie M, Kelly JM, George MW (2007) 'Solvent dependent photophysics of fac-[Re(CO)(3)(11,12-X(2)dppz)(py)](+)(X = H, F or Me)'. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 6 (7):741-748 [DOI] [Details]
2006 'Adsorption and activity of a domoic acid binding antibody fragment on mesoporous silicates'
Hu, XJ; Spada, S; White, S; Hudson, S; Magner, E; Wall, JG (2006) 'Adsorption and activity of a domoic acid binding antibody fragment on mesoporous silicates'. JOURNAL OF PHYSICAL CHEMISTRY B, 110 (37):18703-18709 [DOI] [Details]
2006 'Quantitative TEM analysis of a hexagonal mesoporous silicate structure'
Hudson, S; Tanner, DA; Redington, W; Magner, E; Hodnett, K; Nakahara, S (2006) 'Quantitative TEM analysis of a hexagonal mesoporous silicate structure'. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 8 (29):3467-3474 [DOI] [ULIR Link] [Details]
2005 'Methodology for the immobilization of enzymes onto mesoporous materials'
Hudson, S; Magner, E; Cooney, J; Hodnett, BK (2005) 'Methodology for the immobilization of enzymes onto mesoporous materials'. JOURNAL OF PHYSICAL CHEMISTRY B, 109 (41):19496-19506 [DOI] [Details]
2003 'The photophysics of fac-[Re(CO)3(dppz)(py)]+ in CH3CN: a comparative picosecond flash photolysis, transient infrared, transient resonance Raman and density functional theoretical study'
Dyer J, Blau WJ, Coates CG, Creely CM, Gavey JD, George MW, Grills DC, Hudson S, Kelly JM, Matousek P, McGarvey JJ, McMaster J, Parker AW, Towrie M, Weinstein JA (2003) 'The photophysics of fac-[Re(CO)3(dppz)(py)]+ in CH3CN: a comparative picosecond flash photolysis, transient infrared, transient resonance Raman and density functional theoretical study'. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2 (5):542-554 [Details]

Conference Publications

  Year Publication
2005 Microscopical Society of Ireland 29th Annual Symposium
Hudson S., Tanner D.A., Redington W., Magner E, Hodnett, K. and Nakahara S. (2005) A TEM analysis of mesoporous silicate structure . In: N/A eds. Microscopical Society of Ireland 29th Annual Symposium DIT, Dublin, Ireland, , 07-SEP-05 - 09-SEP-05 , pp.12-12 [Details]
2005 Europacat
Hudson, S., Hodnett, B.K., Cooney, J., and Magner, E. (2005) Generation of novel immobilized enzyme biocatalyts . In: * eds. Europacat , 28-AUG-05 - 01-SEP-05 , pp.*-* [Details]
2005 Europacat-VII, Seventh European Congree on Catalysis
Hudson S., Magner E., Cooney J. and B.K. Hodnett (2005) Generation of novel immobilized enzyme biocatalysts . In: * eds. Europacat-VII, Seventh European Congree on Catalysis , 28-AUG-05 - 01-SEP-05 , pp.231-231 [Details]
2005 nanoSMat2005, International conference on Surfaces, Coatings and Nanostructured Material
Hudson S., Magner E., Cooney J. and Hodnett, B.K. (2005) Generation of novel immobilized enzyme biocatalysts . In: * eds. nanoSMat2005, International conference on Surfaces, Coatings and Nanostructured Material , 07-SEP-05 - 09-SEP-05 , pp.27-27 [Details]
2005 Biotrans 2005 Symposium, The key to Industrial Biotechnology
Hudson S., Goradia D., White S., Cooney J., Hodnett B.K. and E. Magner (2005) Enzymes in Mesoporous Silicates . In: * eds. Biotrans 2005 Symposium, The key to Industrial Biotechnology , 03-JUL-05 - 08-AUG-05 , pp.211-211 [Details]
2005 Biotrans 2005 7th International Symposium on Biocatalysis and Biotransformations
Hudson, S., Hodnett, B.K., Cooney, J., Magner, E. (2005) Generation of novel immobilised enzyme biocatalysts . In: Straathof, A., van der Lans, R., Franssen, M., and Sheldon, R eds. Biotrans 2005 7th International Symposium on Biocatalysis and Biotransformations , 03-JUL-05 - 08-JUL-05 , pp.163-163 [Details]
2007 Bionanotechnology session, American Institute of Chemical Engineering 2007 Annual Meeting
Hudson, S. and E. Magner. (2007) Haem Proteins In Nonaqueous Solvents: Electrochemistry And Biocatalysis Bionanotechnology session, American Institute of Chemical Engineering 2007 Annual Meeting , 04-NOV-07 - 09-NOV-07 [Details]
2007 8th International Symposium on Biocatalysis and Biotransformations
Hudson, S., J. Cooney, B. K. Hodnett and E. Magner. (2007) Chloroperoxidase on Periodic Mesoporous Organosilanes: Immobilisation and Reuse 8th International Symposium on Biocatalysis and Biotransformations , 08-JUL-07 - 13-JUL-07 [Details]
2009 33rd Annual MSI Meeting
Tanner D. A. Nakahara S. Hudson S. Magner E. Redington W. Hodnett K. (2009) Defocus Contrast Image of Hexagonally-Ordered Mesoporous Material 33rd Annual MSI Meeting University College Dublin, Dublin, , 26-AUG-09 - 29-AUG-09 [Details]
2006 COLL 488-Proteins in mesoporous silicates
Hudson, S; White, S; Essa, H; Goradia, D; Cooney, J; Hodnett, BK; Magner, E (2006) Proteins in mesoporous silicates COLL 488-Proteins in mesoporous silicates [Details]

Reviews

  Year Publication
2008 Proteins in Mesoporous Silicates.
Hudson, S; Cooney, J; Magner, E (2008) Proteins in Mesoporous Silicates. Reviews [DOI] [Details]

Honours and Awards

  Year Title Awarding Body
1997 Foundation Scholar of Trinity College Dublin Trinity College Dublin
2019 Marie Curie ITN EID EU Horizon 2020
2019 Disruptive Technologies Award Government of Ireland
2014 SFI Career Development Award Science Foundation Ireland
2017 SFI Infrastructure Award Science Foundation Ireland
2005 BOC Gases Post Graduate Bursary Department of Chemical and Environmental Sciences, University of Limerick
2006 Marie Curie Outgoing International Fellowship European Union
2007 Best Post-graduate Web of Science Journal Publication MSSI, University of Limerick
2012 Fast Moving Front paper Thomson Reuters ScienceWatch
2012 Principal Supervisor of an IRCSET Student IRCSET
2013 Academic Partner in Enterprise Ireland Commercialisation Grant Enterprise Ireland
2013 PI in the Synthesis and Solid State Pharmaceutical Centre Science Foundation Ireland
2013 MSSI Innovation Award MSSI, University of Limerick

Professional Associations

  Association Function From / To
Marie Curie Alumni Association Member 01-MAR-14 / 23-APR-14

Education

  Year Institution Qualification Subject
2013 University of Limerick Diploma Specialist Diploma in Teaching, Learning and Scholarship
2006 University of Limerick PhD Chemistry
2000 Trinity College Dublin Masters by research Chemistry
1999 Trinity College Dublin BA (Mod) Chemistry

Outreach Activities

  Description

Volunteered at the St Vincent de Paul grind school in Moyross 2011-2012

School placement tutor for training education students 2012-present

Teaching Interests

Sarah is a lecturer in Physical and General Chemistry to undergraduate chemistry students. She also is coordinator for the core chemistry curriculum for training second level chemistry teachers, including chemistry pedagogy. She has engaged in peer observation exercises with colleagues from the Civil and Mechanical engineering departments and have worked on integrating their suggestions for problem based and self directed learning into her own teaching style. She engages with technology during lectures, where advantageous and appropriate, e.g. using clicker quizzes to motivate student participation and promote class discussion on topics. Her ambition is to stimulate a passion, or at least a curiosity, in her students and strives to do this by emphasizing the importance and relevance of each topic for life and their education.

Modules Taught

  Term (ID)) Title Link Subject
2020 Pharmaceutical Formulation CH4417Design and manufacture of (bio)pharmaceuticals
2020 Physical Chemistry 2 CH4003Chemical Kinetics
2020 Physical Chemistry 1 CH4041Thermodynamics and Kinetics
Autumn 2013 General Chemistry CH701Tutorials for Students with no Chemistry at Leaving Certificate
Autumn 2013 Introduction to Industrial Biochemistry BC4401Enzyme Catalysis
Spring 2012 Physical Chemistry CH4002
Spring 2012, 2013 Science Teaching 3 SE4006/EY4046 Chemistry Pedagogy
Spring 2013 Analytical Chemistry for the Environment CH4054
Spring 2013 Physical Chemistry CH4054