Snelling, William J. and Moran, Anthony P. and Ryan, Kieran A. and Scully, Paul and McGourty, Kieran and Cooney, Jakki C. and Annuk, Heidi and O'Toole, Paul W.

2007

HorB (HP0127) is a gastric epithelial cell adhesin

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The Helicobacter pylori protein HorB (encoded by HP0127) is a member of a paralogous family that includes the adhesins BabA, AlpA, AlpB, and HopZ, which contribute to adhesion to gastric epithelial cells. Of the verified H. pylori porins, the HorB sequence is most similar to that of HopE, but the function of HorB is unknown. The aim of our study was to investigate the role of HorB in H. pylori gastric epithelial cell adhesion.