This paper provides a brief overview of recent research activities by Mobile & Marine Robotics Research Centre (MMRRC) research team focused toward development of user interfaces for interaction with heterogeneous vehicles in smart Cyber-Physical Systems (CPS). The system, which is currently in development, include both classical user interface elements but also a set of novel "natural" multi-modal user interfaces based on exploration and integration of the state-of-the-art emerging technologies, including Virtal Reality (VR) headsets, spatial tracking devices, 6 DoF input devices, hand gesture recognition devices and touch screens.