Non-fermenting Gram-negative bacteria are problematic in clinical locations, being one of the most

prevalent causes of nosocomial infections. Many of these non-fermenting Gram-negative bacteria

are opportunistic pathogens that affect patients that are suffering with underlying medical

conditions and diseases. Brevundimonas spp., in particular Brevundimonas diminuta and

Brevundimonas vesicularis, are a genus of non-fermenting Gram-negative bacteria considered of

minor clinical importance. Forty-nine separate instances of infection relating to Brevundimonas spp

were found in the scientific literature along with two pseudo-infections. The majority of these

instances were infection with Brevundimonas vesicularis (thirty-five cases – 71%). The major

condition associated with Brevundimonas spp infection was bacteraemia with seventeen individual

cases/outbreaks (35%). This review identified forty-nine examples of Brevundimonas spp. infections

have been discussed in the literature. These findings indicate that infection review programs should

consider investigation of possible Brevundimonas spp outbreaks if these bacteria are clinically

isolated in more than one patient.