© Springer-Verlag Berlin Heidelberg 2014. Connected Health involves the use of ICT to improve healthcare quality and outcomes. In a connected heath environment, stakeholders can struggle to make best use of this information coming from a variety of sources. Given this, we are investigating the challenge of how to use available information to make informed decisions about the care pathway which the patient should follow to ensure that prevention and treatment services are efficient and effective. In this paper, we outline our research into care pathway and information modelling in a Connected Health setting. The research is currently underway, and follows a series of stages using sources in industry and academia. In this paper, we present an overview of the project work packages including an explanation on how the different stages of the research form a continuum in which the developed models will be continually adjusted. We describe how empirical evidence will be used in the development of the models through following an evolutionary multi-method research approach.