Conference Publication Details
Mandatory Fields
Kenny S.;Buggy M.;Pembroke T.;Hill R.;Hatton P.
Key Engineering Materials
In vitro response of osteoblast-like cells to hydroxyapatite-zinc oxide-poly(acrylic acid) cements
2002
February
Published
1
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Optional Fields
347
352
The responses of an osteoblast-like cell line to hydroxyapatite-zinc oxide-polyalkonate cement composites were investigated. The experiments demonstrated that zinc-based cements were cytotoxic in vitro under certain conditions. The setting of these cements involved neutralisation of acid groups on the water-soluble polyacrylic acids (PAA) by the base consisting of zinc oxide or a mixture of zinc oxide and hydroxyapatite (HA). It was found that as the HA content of the cements increased, an increase in the dissolution behaviour of the cements occurred.
Grant Details