Low back pain (LBP) is the leading cause of disability worldwide. Various approaches to diagnose and manage LBP have arisen, leading to an exponential increase in health care costs. Paradoxically, this trend has been associated with a concurrent increase in disability and chronicity. The health care system faces enormous challenges, with both the disability burden and financial impact relating to LBP escalating. Growing evidence suggests that current practice is discordant with contemporary evidence, and is in fact often exacerbating the problem. Change will demand a cultural shift in LBP beliefs and practice. J Orthop Sports Phys Ther 2016;46(11):932-937. doi:10.2519/jospt.2016.0609.