Peer-Reviewed Journal Details
Mandatory Fields
Gordon, BR;McDowell, CP;Lyons, M;Herring, MP
2021
February
Journal Of Affective Disorders
Resistance exercise training among young adults with analogue generalized anxiety disorder
Published
8 ()
Optional Fields
PHYSICAL-ACTIVITY MOOD DISORDERS METAANALYSIS RELIABILITY PREVALENCE SYMPTOMS
281
153
159
Introduction: The objective of this randomized controlled trial (RCT) was to quantify the effects of eight weeks of World Health Organization and American College of Sports Medicine guidelines-based resistance exercise training (RET) among participants meeting criteria for subclinical, or analogue-GAD (AGAD) Methods: Forty-four participants (mean age (y): 25.4.6 +/- 4.9.2) were randomized to either an eight-week, fullysupervised, one-on-one RET intervention or wait-list control. AGAD status was determined using validated cutscores for both the Psychiatric Diagnostic Screening Questionnaire-GAD subscale (>= 6) and Penn State Worry Questionnaire (>= 45). Remission, based on change in AGAD status, was assessed post-intervention, and quantified with number needed to treat (NNT). Primary analyses focused on participants missing outcome data at <= 1 time point (RET: n=12, Wait-list: n=15). RM-ANCOVA examined differences between RET and wait-list across time. Simple effects analysis decomposed significant interactions. Hedges' d quantified magnitude of differences in change between conditions over time. Results: Attendance was 81% and compliance to the RET was 77%. Participants significantly increased strength (all d >= 1.24, p <= 0.006) with no adverse events. RET improved AGAD status (NNT=3, 95%CI: 2 to 7). Significant group X time interactions were found for worry (F-(3,F-66) = 3.12, p <= 0.043; d=0.93, 95%CI: 0.13 to 1.73) and anxiety symptoms (F-(3,F-57.84)=2.91, epsilon=0.88, p <= 0.045; d=0.71, 95%CI: -0.08 to 1.49). RET significantly reduced worry (mean difference=-6.49, p <= 0.045) and anxiety symptoms (mean difference=-10.50, p <= 0.001). Limitations: Limitations include a small sample size, and lack of attention-matched control condition. Conclusion: RET significantly improved AGAD severity, and elicited large, clinically meaningful improvements in worry and anxiety symptoms among young adults with AGAD.
AMSTERDAM
0165-0327
10.1016/j.jad.2020.12.020
Grant Details